Assist. Prof. Đorđe Đukanović
Assistant Professor
Teacher - II-4
Faculty of Medicine
Department
- Medicinski fakultet - Katedra za farmaceutsku hemiju
Courses
Faculty of MedicineBibliography
Journal papers
Ursodeoxycholic Acid Attenuates Lipopolysaccharide-Induced Myocardial Injury by Inhibiting Oxidative Stress, Inflammation, and Apoptosis: The Interplay of Sirt1/Nrf2 and Akt/NF-κB Signaling Pathways.
| DOI | 10.3390/ijms27062843 |
|---|---|
| Journal | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
| Year | 2026 |
| Authors | Ranko Škrbić, Tatjana Milivojac, Zorislava Bajić, Tanja Šobot, Snežana Uletilović, Sanja Jovičić, Đorđe Đukanović, Milica Gajić Bojić, Maja Barudžija, Nataša Vojinović, Miloš Stojiljković, Dragan Djuric, Hani Al-Salami, Sergey Bolevich, and Momir Mikov |
| Volumen | 27 |
| Number | 6 |
| Page to | 2843 |
| Web address | https://www.mdpi.com/1422-0067/27/6/2843 |
Early treatment with pyridostigmine alleviates heart failure with preserved ejection fraction (HFpEF) in rats
| DOI | 10.1139/cjpp-2025-0245 |
|---|---|
| Journal | CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY |
| Year | 2026 |
| Authors | Sonja Marinković, Tanja Šobot, Žana Maksimović, Đorđe Đukanović, Snežana Uletilović, Nebojša Mandić-Kovačević, Sanja Jovičić, Milka Matičić, Milica Gajić Bojić, Aneta Stojmenovski, Anđela Bojanić, Dragana Lončar-Stojiljković, Ranko Škrbić, and Miloš Stojiljković |
| Volumen | 104 |
| Number | 1 |
| Page from | 1 |
| Page to | 11 |
| Web address | https://pubmed.ncbi.nlm.nih.gov/41747235/ |
Novel chlorinated oxime K870 protects rats against paraoxon poisoning better than obidoxime
| Journal | Drug and Chemical Toxicology |
|---|---|
| Year | 2026 |
| Authors | Žana Maksimović, Sonja Marinković, Đorđe Đukanović, Nebojša Mandić-Kovačević, Snežana Uletilović, Mladen Duran, KAMIL KUČA, KAMIL MUSILEK, Dragana Lončar-Stojiljković, Ranko Škrbić, and Milos Stoiljkovic |
Ursodeoxycholic Acid Attenuates Lipopolysaccharide-Induced Myocardial Injury by Inhibiting Oxidative Stress, Inflammation, and Apoptosis: The Interplay of Sirt1/Nrf2 and Akt/NF-κB Signaling Pathways
| Journal | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
|---|---|
| Year | 2026 |
| Authors | Nebojša Mandić-Kovačević, Ranko Škrbić, Ljiljana Amidžić, Zorislava Bajić, Milkica Grabež, Snežana Uletilović, Tanja Šobot, Tatjana Milivojac, Sanja Jovičić, Đorđe Đukanović, Maja Barudžija, Milica Gajić Bojić, Nataša Vojinović, Milos Stojiljkovic, Dragan Đurić, Hani Al-Salami, Sergey Bolevich, and Momir Mikov |
Pyridostigmine treatment significantly alleviates isoprenaline-induced chronic heart failure in rats
| DOI | 10.3390/ijms26146892 |
|---|---|
| Journal | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
| Year | 2025 |
| Authors | Sonja Marinković, Tanja Šobot, žana Maksimović, Đorđe Đukanović, Snežana Uletilović, Nebojša Mandić-Kovačević, Sanja Jovičić, Milka Matičić, Milica Gajić Bojić, Aneta Stojmenovski, Anđela Bojanić, Ranko Škrbić, and Miloš Stojiljković |
| Volumen | 26 |
| Number | 14 |
| Page from | 6892 |
| Page to | 6892 |
| Web address | https://pubmed.ncbi.nlm.nih.gov/40725139/ |
Green Extraction Combined with Chemometric Approach: Profiling Phytochemicals and Antioxidant Properties of Ten Species of the Lamiaceae Family
| DOI | doi.org/10.3390/separations12060155 |
|---|---|
| Journal | Separations |
| Year | 2025 |
| Authors | Branislava Teofilović, Emilija Gligorić, Martina Ninić, Saša Vukmirović, Žarko Gagić, Nebojša Mandić-Kovačević, Biljana Tubić, Đorđe Đukanović, and Nevena Grujić-Letić |
| Volumen | 12 |
| Number | 6 |
| Web address | https://www.mdpi.com/2297-8739/12/6/155 |
Liraglutide treatment restores cardiac function after isoprenaline-induced myocardial injury and prevents heart failure in rats
| DOI | 10.3390/life15030443 |
|---|---|
| Journal | Life |
| Year | 2025 |
| Authors | Zorislava Bajić, Tanja Šobot, Aleksandra Šmitran, Snežana Uletilović, Nebojša Mandić-Kovačević, Tanja Cvjetković, Uglješa Maličević, Bojan Stanetić, Đorđe Đukanović, Milka Matičić, Sanja Jovičić, Dragan Đurić, Miloš Stojiljković, and Ranko Škrbić |
| Volumen | 15 |
| Number | 3 |
| Page to | 443 |
| Web address | https://www.mdpi.com/2075-1729/15/3/443 |
Vascular effects of midazolam, flumazenil, and a novel imidazobenzodiazepine MP-III-058 on isolated rat aorta
| DOI | 10.1139/cjpp-2023-0285 |
|---|---|
| Journal | CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY |
| Year | 2024 |
| Authors | Milica Gajić Bojić, Marco Treven, Kamal P Pandey, V V N Phani Babu Tiruveedhula, Anja Santrač, Đorđe Đukanović, Nataša Vojinović, Ljiljana Amidžić, Ranko Škrbić, Petra Scholze, Margot Ernst, James M Cook, and Miroslav M Savić |
| Volumen | 102 |
| Number | 3 |
| Page from | 206 |
| Page to | 217 |
| Web address | https://pubmed.ncbi.nlm.nih.gov/37909404/ |
Effect of folic acid on isoprenaline-induced myocardial injury in rats
| DOI | 10.1556/2060.2023.00291 |
|---|---|
| Journal | PHYSIOLOGY INTERNATIONAL |
| Year | 2024 |
| Authors | Tanja Šobot, Zorislava Bajić, Ranko Škrbić, Snežana Uletilović, Nebojša Mandić-Kovačević, Tanja Cvjetković, Uglješa Maličević, Đorđe Đukanović, Milica Gajić Bojić, Sanja Jovičić, Maja Barudžija, Miloš Stojiljković, and Dragan Đurić |
| Volumen | 111 |
| Number | 1 |
| Page from | 80 |
| Page to | 96 |
| Web address | https://pubmed.ncbi.nlm.nih.gov/38261080/ |
Preparing a Rat Brain Tissue Samples for Acetylcholinesterase Activity Measurement - the MM method
| DOI | 10.5937/scriptamed52-35485 |
|---|---|
| Journal | Scripta Medica |
| Year | 2024 |
| Authors | Sonja T. Marinković, Đorđe Đukanović, Nebojša Mandić-Kovačević, Tanja Cvjetković, Snežana Uletilović, and Žan M. Maksimović |
| Volumen | 52 |
| Number | 4 |
| Page from | 266 |
| Page to | 272 |
| Web address | http://scriptamedica.com/wp-content/uploads/2021/12/04-MARINKOVI%C4%86-et-al.-FINAL.pdf |
Clinical Aspects of Acute Mesenteric Ischaemia
| DOI | 10.5937/scriptamed55-50514 |
|---|---|
| Journal | Scripta Medica |
| Year | 2024 |
| Authors | Zoran Matković, Uglješa Maličević, Milica Gajić Bojić, Aleksandra Krivokuća, Đorđe Đukanović, Nataša Matković, and Zoran Aleksić |
| Volumen | 55 |
| Number | 5 |
| Page from | 623 |
| Page to | 635 |
Design of Novel TRPA1 Agonists Based on Structure of Natural Vasodilator Carvacrol—In Vitro and In Silico Studies
| DOI | 10.3390/pharmaceutics16070951 |
|---|---|
| Journal | PHARMACEUTICS |
| Year | 2024 |
| Authors | Đorđe Đukanović, Relja Suručić, Milica Gajić Bojić, Saša Trailović, Ranko Škrbić, and Žarko Gagić |
| Volumen | 16 |
| Number | 7 |
| Web address | https://www.mdpi.com/1999-4923/16/7/951 |
Cardioprotective Effects of Ursodeoxycholic Acid in Isoprenaline-Induced Myocardial Injury in Rats
| DOI | 10.3390/biom14101214 |
|---|---|
| Journal | Biomolecules |
| Year | 2024 |
| Authors | Dalibor Mihajlović, Đorđe Đukanović, Milica Gajić Bojić, Sanja Jovičić, Nebojša Mandić-Kovačević, Snežana Uletilović, Žana Maksimović M., Nebojša Pavlović, Boris Dojčinović, Sergey Bolevich, Momir Mikov, Ranko Škrbić, Nada Banjac, and Velibor Vasović |
| Volumen | 14 |
| Number | 10 |
| Web address | https://www.mdpi.com/2218-273X/14/10/1214 |
Ursodeoxycholic and chenodeoxycholic bile acids attenuate systemic and liver inflammation induced by lipopolysaccharide in rats
| DOI | 10.1007/s11010-024-04994-2 |
|---|---|
| Journal | MOLECULAR AND CELLULAR BIOCHEMISTRY |
| Year | 2024 |
| Authors | Tatjana Milivojac, Milkica Grabež, Aleksandra Krivokuća, Uglješa Maličević, Milica Gajić Bojić, Đorđe Đukanović, Snežana Uletilović, Nebojša Mandić-Kovačević, Tanja Cvjetković, Maja Barudžija, Nataša Vojinović, Aleksandra Šmitran, Ljiljana Amidžić, Miloš Stojiljković, Miodrag Čolić, Momir Mikov, and Ranko Škrbić |
| Web address | https://pubmed.ncbi.nlm.nih.gov/38578526/ |
Methodological challenges in using human umbilical artery as a model for in vitro studies
| DOI | 10.1113/EP091374. |
|---|---|
| Journal | EXPERIMENTAL PHYSIOLOGY |
| Year | 2023 |
| Authors | Milica Gajić Bojić, Đorđe Đukanović, Sonja Marinković, Sanja Jovičić, Miloš Stojiljković, Dragan Đurić, and Ranko Škrbić |
| Volumen | 08 |
| Number | 12 |
| Page from | 1569 |
| Page to | 1578 |
| Web address | https://pubmed.ncbi.nlm.nih.gov/37837634/ |
Pomegranate Peel Extract Attenuates Isoprenaline-Induced Takotsubo-like Myocardial Injury in Rats
| DOI | 10.3390/pharmaceutics15061697. |
|---|---|
| Journal | PHARMACEUTICS |
| Year | 2023 |
| Authors | Sonja T. Marinković, Đorđe Đukanović, Mladen Duran, Zorislava Bajić, Tanja Šobot, Snežana Uletilović, Nebojša Mandić-Kovačević, Tanja Cvjetković, Žana M. Maksimović, Uglješa Maličević, Nikolina Vesić, Sanja Jovičić, Maja Barudžija, Katarina Šavikin, Dragan M. Đurić, Miloš Stojiljković, and Ranko Škrbić |
| Volumen | 15 |
| Number | 6 |
| Page to | 1697 |
| Web address | https://pubmed.ncbi.nlm.nih.gov/37376144/ |
Methodological challenges in using human umbilical artery as a model for in vitro studies
| DOI | 10.1113/EP091374. |
|---|---|
| Journal | EXPERIMENTAL PHYSIOLOGY |
| Year | 2023 |
| Authors | Milica Gajić Bojić, Đorđe Đukanović, Sonja Marinković, Sanja Jovičić, Miloš Stojiljković, and Ranko Škrbić |
| Volumen | 08 |
| Number | 12 |
| Page from | 1569 |
| Page to | 1578 |
Antioxidative Potential of Pomegranate Peel Extract: In Vitro and In Vivo Studies
| DOI | 10.5937/scriptamed54-43453 |
|---|---|
| Journal | SCRIPTA MEDICA |
| Year | 2023 |
| Authors | Nebojša Mandić-Kovačević, Zoran Kukrić, Staniša Latinović, Tanja Cvjetković, Tanja Šobot, Zorislava Bajić, Uglješa Maličević, Sonja Marinković, Đorđe Đukanović, Snežana Uletilović, and Relja Suručić |
| Volumen | 54 |
| Number | 1 |
| Page from | 9 |
| Page to | 18 |
| Web address | https://scindeks-clanci.ceon.rs/data/pdf/2490-3329/2023/2490-33292301009M.pdf |
Vasorelaxant effect of monoterpene carvacrol on isolated human umbilical artery.
| DOI | 10.1139/cjpp-2021-0736. |
|---|---|
| Journal | CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY |
| Year | 2022 |
| Authors | Đorđe Đukanović, Milica Gajić Bojić, Sonja Marinković, Saša Trailović, Miloš Stojiljković, and Ranko Škrbić |
| Volumen | 100 |
| Number | 8 |
| Page from | 755 |
| Page to | 762. |
| Web address | https://pubmed.ncbi.nlm.nih.gov/35507953/ |
Time-dependent and force-dependent vasoreactivity of isolated human umbilical arteries
| DOI | 10.5937/scriptamed51-28131 |
|---|---|
| Journal | SCRIPTA MEDICA |
| Year | 2020 |
| Authors | Đorđe Đukanović, Milica Gajić Bojić, and Ranko Škrbić |
| Volumen | 51 |
| Number | 3 |
| Page from | 134 |
| Page to | 140 |
| Web address | https://scindeks.ceon.rs/article.aspx?artid=2490-33292003134Q |
Conference papers
ANTIOXIDATIVE CAPACITY OF POMEGRANATE PEEL EXTRACTS: RESULTS OF IN VITRO AND IN VIVO STUDIES
| Scientific Conference | 9th European Section Meeting of the International Academy of Cardiovascular Sciences (IACS) |
|---|---|
| Year | 2026 |
| Authors | Milos Stojiljkovic, Sonja Marinković, Nebojša Mandić-Kovačević, Zoran Kukrić, Staniša Latinović, Tanja Šobot, Zorislava Bajić, Uglješa Maličević, Đorđe Đukanović, Snežana Uletilović, Relja Suručić, and Ranko Škrbić |
The effect of pyridostigmine treatment on two isoprenaline models of heart failure in rats.
| Scientific Conference | Joint International Conference 2026 — International Academy of Cardiovascular Sciences and Society for Nitric Oxide and Allied Radicals. |
|---|---|
| Publication | Abstract Book |
| Year | 2026 |
| Authors | Miloš Stojiljković, Sonja Marinković, Tanja Šobot, Žana Maksimović, Zorislava Bajić, Đorđe Đukanović, Snježana Uletilović, Nebojša Mandić-Kovačević, Sanja Jovičić, Milka Matičić, Milica Gajić Bojić, Aneta Stojmenovski, Anđela Bojanić, Dragana Lončar-Stojiljković, Dragan Đurić, and Ranko Škrbić |
Punica granatum peel extract significantly attenuates the isoprenaline-induced myocardial injury in rats
| Scientific Conference | 8th European Section Meeting of the International Academy of Cardiovascular Sciences (IACS) |
|---|---|
| Year | 2026 |
| Authors | Nikolina Vesić, Uglješa Maličević, Đorđe Đukanović, Tatjana Milivojac, Zorislava Bajić, Tanja Šobot, Snežana Uletilović, Nebojša Mandić-Kovačević, Maja Barudžija, Sanja Jovičić, Ljiljana Amidžić, Milos Stojiljkovic, and Ranko Škrbić |
Pyridostigmine treatment significantly alleviates isoprenaline-induced chronic heart failure in rats
| Scientific Conference | 11th European Section Meeting of the International Academy of Cardiovascular Sciences (IACS) |
|---|---|
| Year | 2026 |
| Authors | Milos Stojiljkovic, Ranko Škrbić, Sonja Marinković, Tanja Šobot, Žana Maksimović, Đorđe Đukanović, Snežana Uletilović, Nebojša Mandić-Kovačević, Sanja Jovičić, Milka Matičić, Milica Gajić Bojić, Aneta Stojmenovski, Anđela Bojanić, and Dragana Lončar-Stojiljković |
Isoprenaline-induced chronic heart failure is alleviated by pyrridostigmine treatment in rats
| Scientific Conference | 11th European Section Meeting of the International Academy of Cardiovascular Sciences (IACS) |
|---|---|
| Year | 2026 |
| Authors | Žana Maksimović, Sonja Marinković, Tanja Šobot, Đorđe Đukanović, Snežana Uletilović, Nebojša Mandić-Kovačević, Sanja Jovičić, Milka Matičić, Milica Gajić Bojić, Aneta Stojmenovski, Anđela Bojanić, Ranko Škrbić, and Milos Stojiljkovic |
Kardiometabolički efekti ekstrakta kore nara: rezultati kliničkih i eksperimentalnih studija
| Scientific Conference | 15.kongres farmakologa Srbije sa međunarodnim učešćem |
|---|---|
| Year | 2026 |
| Authors | Ranko Škrbić, Milkica Grabež, Sonja Trbojević, Zorislava Bajić, Tanja Šobot, Milica Gajić Bojić, Đorđe Đukanović, Mladen Duran, Snežana Uletilović, Nebojša Mandić-Kovačević, Tanja Cvjetković, Uglješa Maličević, Miodrag Čolić, Nataša Miljuš, Dragan Đurić, and Milos Stojiljkovic |
Kardioprotektivni efekat liraglutida u eksperimentalnom modelu izoprenalinske kardiotosičnosti
| Scientific Conference | 15.kongres farmakologa Srbije sa međunarodnim učešćem |
|---|---|
| Year | 2026 |
| Authors | Milos Stojiljkovic, Ranko Škrbić, Zorislava Bajić, Tanja Šobot, Milica Gajić Bojić, Đorđe Đukanović, Snežana Uletilović, Nebojša Mandić-Kovačević, Uglješa Maličević, and Dragan Đurić |
. Isoprenaline-induced chronic heart failure is alleviated by pyridostigmine treatment in rats.
| Scientific Conference | 11th European Section Meeting of the International Academy of Cardiovascular Sciences |
|---|---|
| Year | 2025 |
| Authors | Žana Maksimović, Sonja Marinković, Tanja Šobot, Đorđe Đukanović, Snežana Uletilović, Nebojša Mandić-Kovačević, Sanja Jovičić, Milka Matičić, Milica Gajić Bojić, Aneta Stojmenovski, Andjela Bojanić, Ranko Škrbić, and Milos Stioljkovic |
Evaluation of chenodeoxycholic acid as a cardioprotective agent in isoprenaline-induced myocardial injury.
| Scientific Conference | 11th Annual Meeting of the European Section of the International Academy of Cardiovascular Sciences |
|---|---|
| Publication | Cor Vasa. 2025;67(Suppl 4). |
| Year | 2025 |
| Authors | Đorđe Đukanović, Dalibor Mihajlović, Žana Maksimović, Sonja Marinković, Uglješa Maličević, Snežana Uletilović, Nebojša Mandić-Kovačević, Sanja Jovičić, Zorislava Bajić, Tanja Šobot, Momir Mikov, and Ranko Škrbić |
| Page from | 24 |
| Page to | 25 |
| Web address | https://actavia.e-coretvasa.cz/pdfs/cor/2025/91/01.pdf |
Pyridostigmine treatment significantly alleviates isoprenaline-induced chronic heart failure in rats.
| Scientific Conference | 11th Annual Meeting of the European Section of the International Academy of Cardiovascular Sciences |
|---|---|
| Publication | Cor Vasa. 2025;67(Suppl 4). |
| Year | 2025 |
| Authors | Miloš Stojiljković, Ranko Škrbić, Sonja Marinković, Tanja Šobot, Žana Maksimović, and Đorđe Đukanović |
| Page from | 72 |
Isoprenaline model of chronic heart failure – comparison of the time-dependent functional and structural changes of the myocardium.
| Scientific Conference | 10th Annual Meeting of the European Section of the International Academy of Cardiovascular Sciences |
|---|---|
| Publication | Abstract Collection in Eur Pharm J. |
| Year | 2024 |
| Authors | Sonja Marinković, Žana Maksimović, Tanja Šobot, Đorđe Đukanović, Sanja Jovičić, and Ranko Škrbić |
Vascular effects of midazolam, flumazenil and a novel imidazobenzodiazepine MP-III-058 on isolated rat aorta.
| Scientific Conference | 15. Kongres farmakologa Srbije i 5. kongres kliničke farmakologije Srbije sa međunarodnim učešćem |
|---|---|
| Year | 2023 |
| Authors | Milica Gajić Bojić, Marco Treven, Kamal P Pandey, V V N Phani Babu Tiruveedhula, Anja Santrač, Đorđe Đukanović, Nataša Vojinović, Ljiljana Amidžić, Ranko Škrbić, Petra Scholze, Margot Ernst, James M Cook, and Miroslav M Savić |
The potential cardioprotective effect of bile acids in isoprenaline-induced myocardial injury
| Scientific Conference | 9th International Congress of Pathophysiology and 5th Congress of Physiological Sciences of Serbia with International Participation |
|---|---|
| Year | 2023 |
| Authors | Đorđe Đukanović, Dalibor Mihajlović, Žana Maksimović, Snežana Uletilović, Nebojša Mandić-Kovačević, Tanja Cvjetković, Uglješa Maličević, Milica Gajić Bojić, Nikolina Vesić, Tatjana Milivojac, Aleksandra Krivokuća, Momir Mikov, and Ranko Škrbić |
Vascular effects of midazolam, flumazenil and a novel imidazobenzodiazepine MP-III-058 on isolated rat aorta.
| Scientific Conference | 10. skup Sjevernoameričke sekcije Internacionalne akademije za kardiovaskularne nauke |
|---|---|
| Year | 2023 |
| Authors | Milica Gajić Bojić, Marco Treven, Kamal P Pandey, V V N Phani Babu Tiruveedhula, Anja Santrač, Đorđe Đukanović, Nataša Vojinović, Ljiljana Amidžić, Ranko Škrbić, Petra Scholze, Margot Ernst, James M Cook, and Miroslav M Savić |
Beneficial effects of bile acids on LPS induced acute lung injury in rats
| Scientific Conference | 9th International Congress of Pathophysiology and 5th Congress of Physiological Sciences of Serbia with International Participation |
|---|---|
| Year | 2023 |
| Authors | Tatjana Milivojac, Uglješa Maličević, Aleksandra Krivokuća, Maja Barudžija, Milica Gajić Bojić, Đorđe Đukanović, Snežana Uletilović, Nebojša Mandić-Kovačević, Tanja Cvjetković, Milkica Grabež, and Ranko Škrbić |
The role of TRPA1 channels in regulation of vascular tone - 3D QSAR medeling with desing of novel TRPA1 agonists.
| Scientific Conference | 9. skup Evropske sekcije Internacionalne akademije za kardiovaskularne nauke |
|---|---|
| Year | 2023 |
| Authors | Đorđe Đukanović, Milica Gajić Bojić, Ranko Škrbić, and Žarko Gagić |
Ursodeoxycholic acid attenuates systemic and liver inflammation induced by LPS in rats.
| Scientific Conference | 9. skup Evropske sekcije Internacionalne akademije za kardiovaskularne nauke |
|---|---|
| Year | 2023 |
| Authors | Tatjana Milivojac, Aleksandra Krivokuća, Uglješa Maličević, Maja Barudžija, Milica Gajić Bojić, Đorđe Đukanović, Snežana Uletilović, Nebojša Mandić-Kovačević, Tanja Cvjetković, Milkica Grabež, Aleksandra Šmitran, Mladen Duran, and Ranko Škrbić |
Relaxing effects of imidazobenzodiazepine MP-III-058 on rat aorta and trachea.
| Scientific Conference | 8. skup Evropske sekcije Internacionalne akademije za kardiovaskularne nauke |
|---|---|
| Year | 2022 |
| Authors | Milica Gajić Bojić, V V N Phani Babu Tiruveedhula, Sonja Marinković, Đorđe Đukanović, Ranko Škrbić, James M Cook, and Miroslav M Savić |
The role of the TRP channels in carvacrol-induced vasodilatation of human mesenteric arteries
| Scientific Conference | 8. skup Evropske sekcije Internacionalne akademije za kardiovaskularne nauke |
|---|---|
| Year | 2022 |
| Authors | Đorđe Đukanović, Milica Gajić Bojić, Sanja Marinković, and Ranko Škrbić |
Carcacrol-induced vasodilatation of isolated human umbilical arteries - blocking the L-type calcium channles.
| Scientific Conference | 7. skup Evropske sekcije i 8. skup Sjevernoameričke sekcije Internacionalne akademije za kardiovaskularne nauke |
|---|---|
| Year | 2021 |
| Authors | Đorđe Đukanović, Sonja Marinković, Milica Gajić Bojić, Saša Trailović, Miloš Stojiljković, and Ranko Škrbić |
Projects
International
Antioksidativni potencijal biljaka iz porodice Lamiaceae
Porodica cvetnica Lamiaceae predstavlja jednu od najrasprostranjenijih porodica biljaka koju karakteriše visok sadržaj fenolnih kiselina i flavonoida i značajna antioksidativna aktivnost. Sve više ljudi razmatra upotrebu začina i bilja za medicinsku i terapeutsku upotrebu, posebno za različita hronična stanja. Dijabetes melitus je hronična, metabolička bolest od koje pati oko 422 miliona ljudi širom sveta...
| Project Number | 1257049 |
|---|---|
| Status | Not archived |
| Type of project | International Research - Other |
| Organizational unit | Faculty of Medicine |
| Head | Assoc. Prof. Zarko Gagic |
| Participants |
Nebojsa Mandic-Kovacevic Assoc. Prof. Biljana Tubic Assist. Prof. Djordje Djukanovic |
| Business Partner | AUTONOMNA POKRAJINA VOJVODINA,POKRAJINSKI SEKRETARIJAT ZA VISOKO OBRAZOVANJE I NAUČNOISTRAŽIVAČKU DJELATNOST |
| Beginning of realization | 2023-03-01 |
| End of the project | 2024-03-31 |
| Project value | 4918.0 BAM |
Other
Potencijal primjene karvakrola iz prirodnih izvora u terapiji kardiovaskularnih oboljenja - značaj TRPA1 kanala i dizajn novih jedinjenja sa vazodilatatornim dejstvom
Među hroničnim nezaraznim bolestima, kardiovaskularna oboljenja jedan su od glavnih uzročnika smrtnosti u razvijenim zemljama. Biljke iz porodice Labiateae među kojima se nalazi i origano primjenjuju se tradicionalno kod osoba oboljelih od hipertenzije. Ekstrakti biljaka iz roda Origanum pokazali su vazodilatatorno dejstvo u in vitro i u in vivo studijama na laboratorijskim životinjama. Jedan od glavnih aktivnih ...
| Project Number | 1257059 |
|---|---|
| Status | Not archived |
| Type of project | National Research |
| Organizational unit | Faculty of Medicine |
| Head | Assoc. Prof. Zarko Gagic |
| Participants | Maja Trisic Assoc. Prof. Biljana Tubic Nikolina Nedinic Assist. Prof. Djordje Djukanovic Nebojsa Mandic-Kovacevic Anastasija Radojicic Ugljesa Malicevic |
| Business Partner | Ministarstvo za naučnotehnološki razvoj i visoko obarzovanje Republike Srpske |
| Beginning of realization | 2024-03-01 |
| End of the project | 2026-03-01 |
| Project value | 4000.0 BAM |
Ispitivanje uticaja žučnih kiselina i statina na kardiotoksičnost izazvanu doksorubicinom u in vivo sistemu
Kardiotoksičnost uzrokovana antraciklinima je poznata komplikacija onkološke terapije, bez dostupne efikasne i sigurne terapije u prevenciji njenog nastanka. Najčešće se manifistuje kao odložena kardiovaskularna bolest/disfunkcija usljed kumulativne doze antraciklina. Doksorubicin je široko zastupljen antraciklin u terapiji adultnih i pedijatrijskih maligniteta.
| Project Number | 1257024 |
|---|---|
| Status | Not archived |
| Type of project | National Research |
| Organizational unit | Faculty of Medicine |
| Head | Prof. Lana Nezic |
| Participants | Svetlana Golocorbin-Kon Assoc. Prof. Ljiljana Amidzic Prof. Momir Mikov Assist. Prof. Djordje Djukanovic Vesna Jacevic Biljana Vatres Assoc. Prof. Natasa Bubic Pajic Vesna Vujic-Aleksic Assist. Prof. Zana Radic Savic |
| Beginning of realization | 2020-07-01 |
| End of the project | 2022-07-31 |
| Project value | 25000.0 BAM |
Prirodni proizvodi kao inhibitori neuropilin-1 receptora: uloga u SARS-CoV-2 infekciji
Cilj ovog istraživanja je proučavanje prirodnih proizvoda koji mogu inhibirati interakciju S-glikoproteina SARS-CoV-2 sa neuropilin-1 (NRP-1) receptorom, što predstavlja novi pristup u prevenciji i tretmanu COVID-19. Istraživanje se zasniva na nedavno objavljenim rezultatima koji pokazuju da određeni mali molekuli, kao što su folna kiselina i leukovorin, imaju potencijal za blokiranje ove interakcije kroz stabilno vezivanje za b1 domen NRP-1. Metodologija uključuje spektrofotometrijske ...
| Project Number | 1257072 |
|---|---|
| Status | Not archived |
| Type of project | National - Other |
| Organizational unit | Faculty of Medicine |
| Head | Assoc. Prof. Relja Surucic |
| Participants |
Prof. Ranko Skrbic Nevena Jokic Assoc. Prof. Maja Travar Assoc. Prof. Mirjana Djermanovic Assist. Prof. Djordje Djukanovic Mladen Duran Milica Gajic Andjela Bojanic |
| Business Partner | Ministarstvo za naučnotehnološki razvoj i visoko obarzovanje Republike Srpske |
| Beginning of realization | 2025-01-01 |
| End of the project | 2025-12-01 |
| Project value | 9000.0 BAM |
Bezbjednost, antioksidativna aktivnost i kariogeni potencijal komercijalnih i magistralno izrađenih biljnih sirupa koji se koriste u terapiji kašlja kod djece u Republici Srpskoj
Prva faza istraživanja će obuhvatiti pregled, kategorizaciju i komparativnu analizu bezbijednosti ekscipijenasa i biljnih ekstrakata koji ulaze u sastav komercijalnih i magistralno izrađenih biljnih sirupa koji se koriste u terapiji kašlja kod djece u Republici Srpskoj...
| Project Number | 1257065 |
|---|---|
| Status | Not archived |
| Type of project | National Research |
| Organizational unit | Faculty of Medicine |
| Head | Assist. Prof. Biljana Gataric |
| Participants |
Aleksandra Krivokuca Aneta Stojmenovski Nebojsa Mandic-Kovacevic Assist. Prof. Djordje Djukanovic Assoc. Prof. Zarko Gagic |
| Business Partner | Ministarstvo za naučnotehnološki razvoj i visoko obarzovanje Republike Srpske |
| Beginning of realization | 2025-03-01 |
| End of the project | 2027-03-01 |
| Project value | 8000.0 BAM |
"Efekti sulftno-sulfitne mineralne vode na biološke parametre koštanog metabolizma u eksperimentalnoj osteoporozi kod pacova"
Ispitivanje uticaja sulfatno-sulfitne miniralne vode na biološke parametre koštanog metabolizma u eksperimentalnoj osteoporozi ko pacova. Cilj projekta da se detaljno ispitaju molekularni mehanizmi djelovanja sulfatno-sulfitne mineralne vode u regulisanju koštane homeostaze na eksperimentalnom modelu osteoporoze izazvane ovariektomijom kod ženki pacova.
| Project Number | 1257031 |
|---|---|
| Status | Not archived |
| Type of project | National Research |
| Organizational unit | Faculty of Medicine |
| Head | Prof. Ranko Skrbic |
| Participants |
Prof. Svjetlana Stoisavljevic Satara Suzana Petkovic Assist. Prof. Djordje Djukanovic Assoc. Prof. Tamara Popovic Assoc. Prof. Natasa Stojakovic Prof. Milos Stojiljkovic Boris Prodanovic |
| Business Partner | Ministarstvo za naučnotehnološki razvoj, visoko obrazovanje i informaciono društvo |
| Beginning of realization | 2019-12-01 |
| End of the project | 2021-12-31 |
| Project value | 23000.0 BAM |
